New Findings Recommend Oestrogen Therapy After Surgical Menopause

Published: 16th June 2020

New findings, published by Yale University Professor Philip Sarrel, recommend oestrogen therapy after surgical menopause as a way to effectively control symptoms, as well as reducing the risk of future disease. In this article, Prof Sarrel also explores how HRT can reduce medical expenditure for women following a hysterectomy.

“Menopause” is a monthly medical journal published by the North American Menopause Society. After editorial review, it publishes new findings from studies by the world’s leading scientific researchers. Menopause journal, in its more than 25 years of publication, has gained recognition as one of the most respected and highly rated of medical journals.

The June 2020 issue of Menopause journal contains a new article based on long-term data (18 year follow-up) from the Women’s Health Initiative (WHI) Studies. The authors select out the data for women who initiated estrogen therapy following hysterectomy and or removal of their ovaries before age 60. For these women, using estrogen therapy reduced disease risks for coronary heart disease, breast cancer, colorectal cancer, hip fracture, and stroke.

Earlier reports from the WHI study showed the use of estrogen therapy before age 60 reduced mortality due to breast cancer, heart disease and Alzheimer’s disease (Manson J and others, Ann Intern Med. 2019; LaCroix A and others, JAMA 2011). The findings are consistent with the 30 year follow-up studies from the Mayo Clinic Oophorectomy Study. That study also adds reduced risk for dementia when women initiate estrogen therapy at the time of surgery and continue for 10 years or more.

Disease risk and mortality rates before age 70 are increased following surgical menopause without hormone therapy. Women and healthcare providers think and use hormone therapy primarily for control of symptoms due to menopause. It is as, if not more, important to realize estrogen therapy in particular should be used for disease prevention and extending life expectancy.

The Menopause: June 2020 issue also carries an Invited Editorial by Yale Professor Philip Sarrel which comments on the new WHI findings and expands upon the issues of reducing medical expenditures and disease prevention through the use of estrogen therapy.

Further discussion by Professor Sarrel is available on the empowHER website.

Click here to read the full article


Newson Health Menopause and Wellbeing Centre was launched in 2018 by leading menopause specialist and GP, Dr Louise Newson. Created to help women receive the most appropriate, individualised and holistic treatment for their perimenopause and menopause, it has quickly become a centre of excellence, providing care to women of all ages, both via remote consultations and in-person at clinics in Stratford-upon-Avon, Warwickshire and Lymm, Cheshire.

A passionate and tireless campaigner for better menopause care for all women, Dr Newson has also founded the Menopause Doctor website, The Menopause Charity, the balance app, Newson Health Research and Education and written a best-selling Haynes Manual on Menopause.

The Menopause Doctor website is a free resource providing a huge amount of unbiased, evidence based information about the menopause and perimenopause for women and healthcare professionals. The site has been adopted by the Royal College of GPs (RCGP) as an official educational library for menopause. Visit www.menopausedoctor.co.uk.

The Menopause Charity was founded in 2020, with trustees including sustainable health expert Professor Matthew Cripps and media ambassadors Davina McCall, Lorraine Kelly, Liz Earle and Meg Mathews. The charity has many exciting plans to help women and their families and colleagues with the challenges caused by the menopause, including an educational website, professionally staffed helpline and fundraising for research activities. Visit www.themenopausecharity.org.

‘balance’ is a free app that was developed to enable women to track their symptoms, access personalised expert content, share stories and lots more. Get the balance app at www.balance-app.com.

Newson Health Research and Education is a not-for-profit organisation from which all profits are invested back into the business. A Confidence in Menopause educational platform has been developed specifically for healthcare professionals and can be found at https://www.fourteenfish.com/menopause/subscribe

The Haynes Manual on Menopause is a definitive guide to help women, their partners and families cut through the plethora of misinformation and take a straightforward look at menopause. Find out more at www.newsonhealth.co.uk/resources/menopause-manual.